Up to 6,000 runners are ready to cut a dash in this year's Asda Foundation York 10K 2013.
The amateur athletes are limbering up for the event on Sunday 4th August - the fifth annual York 10K to be organised by Jane Tomlinson's Run For All.
Starting and finishing on The Knavesmire, the run has been described as the 'UK's most beautiful city run'. Its picturesque route take runners past the city's most famous sights including York Minster, the city walls and landmarks like Clifford's Tower and the Shambles.
As well as supporting the Jane Tomlinson Appeal, other charities to benefit from the final Run For All 10K of the 2013 season will be Macmillan Cancer Support, Martin House Children's Hospice, Sue Ryder, Candlelighters, Yorkshire Cancer Resarch, York Teaching Hospital Charity, Brain Tumour Research and Support across Yorkshire and Clic Sargent.
Among those running will be BBC Sports presenter Eleanor Oldroyd - taking part in her first 10K - and much-loved regional news anchorman Harry Gration who is using the event as a warm-up for The Plusnet Yorkshire Marathon this October.
Eleanor, 51, explained how she came to be involved in the event: "I've never been someone who's very sporty and it's been a constant battle to get more active.
"I got to know Jane a bit when she won the Helen Rollason Sports Personality of the Year award as I was on the judging panel. After she died I got to know Mike and the family.
"I was blown away by her incredible spirit and determination and that she was able to push herself to extraordinary lengths. She was a remarkable woman.
"The training has gone really well so far. I've gone back to the gym and I'm lighter and fitter than I was in my 30s. I'm really looking forward to race day."
Other participants will include Keisha Meek, 21, who will run in memory of her father Ian, who carried the Olympic Torch through York last year and raised an incredible £110,000 for brain tumour research before his death.
Keisha said: "My dad was diagnosed with a brain tumour in 1994 and it became cancerous in 2009. He took part in all sorts of charitable events before his death and I want to keep his legacy going by doing my bit."
Devoted dad Mike Francis will run the York 10K as a tribute to his son Guy who died in 2002 aged just 23. Mike of Acomb, York, will raise funds to support the Guy Francis Research Fund which aims to help other bone cancer sufferers.
Run For All Event Lead Charlie Tatman said: "The York 10K always throws up some really inspirational stories and we're looking forward to another great year.
"We hope that everyone has a fantastic day and raises lots of money for their chosen charities."
The event is sponsored by the Asda Foundation, Morrison Utility Services, York City Council, BBC Radio York, The York Press and Lucozade.
Asda IPL director Nick Scrase, who is running the York 10K, said: "The York 10K is such a great feel-good event which not only encourages people to get out there and get active, but also to raise funds for a charity of their choice.
"It's always great on race day to see the whole city come alive. And it is particularly heart-warming to see all those people with their charity T-shirts, showing just what cause they are supporting.
"I'm really looking forward to this Sunday's event and wish all my fellow competitors good luck!"
The event also includes the Morrison Utility Services York 10K Corporate Challenge in which around 250 businessmen and women will vie to have their team crowned the fastest.
Among the corporate challenge entrants is a 25-strong team from Enterprise Rent-A-Car who are raising money for the Jane Tomlinson Appeal. A team of 14 took part for the first time last year and raised £1,400 for the cause. Enterprise Rent-A-Car added another £2,500 to that total.
Brian Waligora, Enterprise Rent-A-Car, said: "At Enterprise we are fully committed to supporting the local communities surrounding our branches and by supporting local causes such as the Jane Tomlinson Appeal we can really begin to give back to those communities."
John Edwards, Morrison Utility Services Contract Director, said: "We are delighted to continue our association with the York 10K for the fifth year. It is a fantastic event which raises significant and much-needed funds for a broad range of charities, both locally and nationally.
"We have been involved since the first race in 2009, and we have been delighted to see more and more companies taking part each year. The enthusiasm of the teams and sense of achievement at the end of the race makes the event really special."
And around 500 children will take part in their own running event - the Arena Group York 10K Mini and Junior Run. Thanks to the generous continued sponsorship of the Arena Group every child is able to run for free.
Adrian Fitzpatrick, managing director of Arena Group, said: "We're so thrilled to be once again supporting the Arena Group York Junior and Mini Run, allowing every child to take part for free.
"It's such a heart-warming event that not only encourages young people to get involved in sport and physical activity - but also instils in them the idea of supporting charity from an early age.
"It's very fitting that this year's chosen cause is the children's ward at York Hospital and we hope that the hospital receives a great boost from the event."
Lord Mayor of York, Councillor Julie Gunnell, will be helping to start the event, as well as volunteering on the day.
She said: "The whole city looks forward to the York 10K every year. To see more than 5,000 runners take to the streets is quite a sight. It's also very heart-warming to know that many of them will be running to raise funds for charity. I wish all everyone taking part in Sunday's York 10K the very best of luck - I'll be there to cheer you on."
Participants can enter the York 10K until 9am on Friday 2nd August. For more details go to www.runforall.com